The effect of vitamin and mineral supplementation on sports performance - ergogenic effect

October 25, 2025Michal Jetelina

Vitamins and minerals are essential micronutrients that enable hundreds of enzymatic reactions in the body.
Unlike macronutrients, they do not provide energy , but without them , energy metabolism, neuromuscular activity, and regeneration could not occur effectively .

In athletes, their needs may be slightly higher due to:

  • accelerated metabolism,

  • higher production of free radicals,

  • adaptation of muscle tissue,

  • and partly due to mineral losses through sweat.

However, supplementation does not automatically lead to improved performance .
If there is no deficit, additional micronutrient intake will not increase performance .

When does supplementation make sense?

The ergogenic effect of micronutrients only occurs when their levels fall below the physiological range .
These are mainly athletes in the following situations:

Risk group Reason Typical deficits
Athletes with low energy intake Weight loss diets, aesthetic sports Iron, calcium, zinc, vitamins B and D
Vegetarians/vegans Low intake of animal sources Iron, B12, zinc
Indoor or winter training Lack of UV radiation Vitamin D
Endurance sports with high sweat rate Long races, heat Sodium (Na) – the main electrolyte lost through sweat
Women and adolescents Growth, menstrual cycle Iron, calcium

Which micronutrients affect performance the most?

Iron (Fe)

Essential for oxygen transport (hemoglobin, myoglobin).
The deficit reduces VO₂max and the ability to regenerate.
Supplementation is only appropriate in cases of proven deficiency (ferritin < 30 µg/l).

B vitamins

Cofactors in carbohydrate, fat and protein metabolism.
Deficiency leads to lower energy efficiency and faster fatigue.
With an adequate diet, supplementation is not necessary.

Vitamin D

It regulates calcium absorption, muscle function and immune response.
Optimal level: 75–100 nmol/l , deficit below 50 nmol/l.
Low levels are associated with a higher risk of stress fractures and reduced muscle strength.


Electrolytes and performance

Electrolytes play a vital role in neuromuscular activity, hydration, and acid-base balance .
According to Jeukendrup & Gleeson (2023), only sodium (Na) is of real importance in terms of performance - other minerals are lost in sweat in small amounts and a regular diet can reliably replace them.

Mineral Main functions Total body stores Typical concentration in sweat Relative importance of losses When to top up Practical recommendation
Sodium (Na) Maintains plasma volume, osmolality, transmission of nerve impulses ~100g 20–80 mmol/l (≈ 460–1840 mg/l) 🔴 High – the main electrolyte lost through sweat At power > 60 min or in heat > 25 °C 300–800 mg Na/l; with extreme sweating up to 1,000–1,500 mg/l
Potassium (K) Maintains the electrical potential of cells, participates in muscle contraction ~140g 3–15 mmol/l (≈ 120–600 mg/l) 🟠 Low – large inventory, small losses Not during exercise; replace with regular diet after exercise Fruits, potatoes, legumes, whole grains
Magnesium (Mg) Enzyme activation, muscle contraction, ATP formation ~25 g (60% in bones) 0.2–1 mmol/l (≈ 5–24 mg/l) 🟢 Very low – losses negligible Not during exercise; suitable after exercise or when intake is low 300–400 mg/day; nuts, seeds, whole grains
Calcium (Ca) Muscle contraction, nerve signaling, bone health ~1,000–1,200 g (99% in bones) 0.1–1 mmol/l (≈ 4–40 mg/l) 🟢 Negligible – minimal losses Not during exercise; important for long-term bone health 800–1,000 mg/day; dairy products, mineral waters, vegetables


Interpretation

  • Sodium (Na) – the only electrolyte whose loss can actually affect performance and hydration.

  • Potassium (K) – losses are small; supplementation during exercise is not necessary.

  • Magnesium (Mg) – losses are very small (5–25 mg/l); important for regeneration, not acute performance.

  • Calcium (Ca) – not significantly lost through sweat; important for long-term bone health.

Is vitamin and mineral supplementation really ergogenic?

From a scientific data perspective:

  • Supplementation is not ergogenic for healthy athletes with adequate nutrient intake.

  • It improves performance only in the case of a deficit - then it restores physiological functions (it does not add a "bonus", but removes the limit).

  • Excess intake can be neutral to counterproductive (e.g., for iron, selenium, vitamins A and D).

In other words:

Micronutrients themselves do not increase performance , but their deficiency limits performance.
Their role is not stimulating, but supportive and necessary to achieve a physiological maximum .

Excess antioxidants (vitamin C, E, selenium) can even dampen post-training adaptation signaling pathways . Therefore, the goal is to have enough, not too much .

A practical approach for athletes

Region Recommendation
Diagnostics Ideally, supplementation should be supported by laboratory tests (ferritin, 25(OH)D, zinc, Mg).
Diet Varied, with plenty of fruits, vegetables, grains, proteins and healthy fats.
Multivitamins Only suitable for athletes with a limited diet, on weight loss diets or when traveling.
Avoid megadoses Excess can interfere with the absorption of other minerals or be toxic.
Food first principle Diet has priority, supplements only according to individual needs.


Summary

  • Vitamins and minerals are essential for energy metabolism, regeneration and immunity.

  • The ergogenic effect of supplementation only occurs when a deficit is corrected , not when there is an excess.

  • Sodium losses are significant, other electrolytes (K, Mg, Ca) are easily replenished in the diet.

  • The best strategy: laboratory control, balanced nutrition, and possibly targeted supplementation.

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Michal JetelinaOctober 25, 2025
Michal JetelinaOctober 25, 2025

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